CHEMISTRY & BIODIVERSITY TOPICAL ISSUE

D-Amino Acid Research in Chemistry, Life Sciences, and Biotechnology.

EDITORIAL : H.Brückner and N. Fujii

Publisher: Verlag Helvatica Chimica Acta

ISSN: 1612-1872

Contents

Editorial
Free and Peptide-Bound D-Amino Acids in Chemistry and Life Sciences (p 1333-1336)
Hans Brüekner, Noriko Fujii

Transpeptidation and Isomerization

Molecular-Dynamics Simulations for Amyloid β_1-42 Monomer with D-Aspartic Acid Residues Using Continuous Solvent (p 1357-1363)
Akifumi Oda, Kana Kobayashi, Ohgi Takahashi

Accumulation of D-β-Aspartic Acid-Containing Proteins in Age-Related Ocular Diseases (p 1364-1370)
Yuichi Kaji, Tetsuro Oshika, Yutaka Takazawa, Masashi Fukayama, Noriko Fujii

Quantification of Structural Alterations of L-Asp and L-Asn Residues in Peptides Related to Neuronal Diseases by Reversed-Phase High-Performance Liquid Chromatography (p 1371-1379)
Yutaka Sadakane, Keiko Konoha, Masahiro Kawahara, Kazuya Nakagomi

SAXS and SANS Observations of Abnormal Aggregation of Human α-Crystallin (p 1380-1388)
Masaaki Sugiyama, Norihiko Fujii, Yukio Morimoto, Keiji Itoh, Kazuhiro Mori, Toshiharu Fukunaga, Noriko Fujii

Review
Collapse of Homochirality of Amino Acids in Proteins from Various Tissues during Aging (p 1389-1397)
Noriko Fujii, Yuichi Kaji, Norihiko Fujii, Tooru Nakamura, Ryota Motoie, Yuhei Mori, Tadatoshi Kinouchi

Influence of Oxidative Stress on D-Aspartyl Endopeptidase Activity (p 1398-1402)
Tadatoshi Kinouchi, Akina Matsuda, Satoru Kawakami, Takahiko Shimizu, Takuji Shirasawa, Noriko Fujii

Structural Consideration of Mammalian D-Aspartyl Endopeptidase (p 1403-1407)
Tadatoshi Kinouchi, Noriko Fujii

Oxidative Stress Induces the Formation of D-Aspartyl Residues in the Elastin Mimic Peptides (p 1408-1412)
Katsunori Kuge, Keiko Kitamura, Koichi Nakaoji, Kazuhiko Hamada, Norihiko Fujii, Takeshi Saito, Noriko Fujii

D-Amino Acid (D-Aspartic Acid) Oxidase

Comparative Characterization of Three D-Aspartate Oxidases and One D-Amino Acid Oxidase from Caenorhabditis elegans (p 1424-1434)
Masumi Katane, Yasuaki Saitoh, Yousuke Seida, Masae Sekine, Takemitsu Furuchi, Hiroshi Homma

Review
D-Aspartate Oxidase: The Sole Catabolic Enzyme Acting on Free D-Aspartate in Mammals (p 1435-1449)
Masumi Katane, Hiroshi Homma

Mutant Mice and Rats Lacking D-Amino Acid Oxidase (p 1450-1458)
Ryuichi Konno, Kenji Hamase, Rindo Maruyama, Kiyoshi Zaitsu

Effects of D-Aspartate Treatment on D-Aspartate Oxidase, Superoxide Dismutase, and Caspase 3 Activities in Frog (Rana esculenta) Tissues (p 1459-1466)
Lavinia Burrone, Marcello Di Giovanni, M. Maddalena Di Fiore, Gabriella Chieffi Baccari, Alessandra Santillo

Thyroid Hormones and D-Aspartic Acid, D-Aspartate Oxidase, D-Aspartate Racemase, H₂O₂, and ROS in Rats and Mice (p 1467-1478)
Enza Topo, George Fisher, Andrea Sorricelli, Francesco Errico, Alessandro Usiello, Antimo D'Aniello

Review
Aberrant Control of Motoneuronal Excitability in Amyotrophic Lateral Sclerosis: Excitatory Glutamate / D-Serine vs. Inhibitory Glycine/γ-Aminobutanoic Acid (GABA) (p 1479-1490)
Jumpei Sasabe, Sadakazu Aiso

D-Amino Acids Related to Nutrition and Industrial Applications

Natural Occurrence and Industrial Applications of d-Amino Acids: An Overview (p 1531-1548)
Sergio Martínez-Rodríguez, Ana Isabel Martínez-Gómez, Felipe Rodríguez-Vico, Josefa María Clemente-Jiménez, Francisco Javier Las Heras-Vázquez

Enzymes Responsible for the Conversion of N^a-[(Benzyloxy)carbonyl]-D-lysine to N^a-[(Benzyloxy)carbonyl]-D-aminoadipic Acid by Rhodococcus sp. AIU Z-35-1 (p 1549-1554)
Kimiyasu Isobe, Nahoko Fukuda, Shouko Nagasawa, Kaoru Saitou

Review
New Biological Functions and Applications of High-Molecular-Mass Poly-γ-glutamic Acid (p 1555-1562)
Haryoung Poo, Chung Park, Mi-Sun Kwak, Doo-Yeol Choi, Seung-Pyo Hong, Il-Han Lee, Yong Taik Lim, Young Ki Choi, Sun-Ryang Bae, Hiroshi Uyama, Chul-Joong Kim, Moon-Hee Sung

Identification and Biochemical Characterization of Membranous Short-Chain Polyglutamate from Bacillus subtilis (p 1563-1572)
Tohru Kamei, Daisuke Yamashiro, Terumi Horiuchii, Yutaka Minouchi, Makoto Ashiuchi

Amino Acid Racemases and Peptide Isomerases

Site-Directed Mutagenesis of Rice Serine Racemase: Evidence That Glu219 and Asp225 Mediate the Effects of Mg²⁺ on the Activity (p 1579-1590)
Yoshitaka Gogami, Ai Kobayashi, Toshihiko Ikeuchi, Tadao Oikawa

Detection and Function of the Intramolecular Disulfide Bond in Arginine Racemase: An Enzyme with Broad Substrate Specificity (p 1591-1602)
Daisuke Matsui, Tadao Oikawa

Mammalian Peptide Isomerase: Platypus-Type Activity Is Present in Mouse Heart (p 1603-1611)
Jennifer M. S. Koh, Stephanie J. P. Chow, Ben Crossett, Philip W. Kuchel

Racemization Mechanisms and Chemistry of D-Amino Acids

Computational Insight into the Mechanism of Serine Residue Racemization (p 1625-1629)
Ohgi Takahashi, Kana Kobayashi, Akifumi Oda

Computational Modeling of the Enolization in a Direct Mechanism of Racemization of the Aspartic Acid Residue (p 1630-1633)
Ohgi Takahashi, Kana Kobayashi, Akifumi Oda

Protein-Engineering Study of Contribution of Conceivable D-Serine Residues to the Thermostabilization of Ovalbumin under Alkaline Conditions (p 1634-1643)
Nobuyuki Takahashi, Maki Maeda, Masayuki Yamasaki, Bunzo Mikami

Generation of Enantiomeric Amino Acids during Acid Hydrolysis of Peptides Detected by the Liquid Chromatography/Tandem Mass Spectroscopy (p 1644-1650)
Tetsuya Miyamoto, Masae Sekine, Tetsuhiro Ogawa, Makoto Hidaka, Hiroshi Homma, Haruhiko Masaki

Photolysis of rac-Leucine with Circularly Polarized Synchrotron Radiation (p 1651-1659)
Uwe J. Meierhenrich, Jean-Jacques Filippi, Cornelia Meinert, Søren V. Hoffmann, Jan Hendrik Bredehöft, Laurent Nahon

Review
Amino Acid Ligand Chirality for Enantioselective Syntheses (p 1660-1669)
Károly Micskei, Tameás Patonay, Luciano Caglioti, Gyula Pályi

Hydrophobicity of Peptides Containing D-Amino Acids (p 1670-1679)
Toratane Munegumi